RSK2 signaling in brain habenula contributes to place aversion learning
نویسندگان
چکیده
منابع مشابه
RSK2 signaling in brain habenula contributes to place aversion learning.
RSK2 is a Ser/Thr kinase acting in the Ras/MAPK pathway. Rsk2 gene deficiency leads to the Coffin-Lowry Syndrome, notably characterized by cognitive deficits. We found that mrsk2 knockout mice are unable to associate an aversive stimulus with context in a lithium-induced conditioned place aversion task requiring both high-order cognition and emotional processing. Virally mediated shRNA-RSK2 kno...
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ژورنال
عنوان ژورنال: Learning & Memory
سال: 2011
ISSN: 1072-0502,1549-5485
DOI: 10.1101/lm.2221011